- Topical therapy - Steroid compounds such as flucinonide (Lidex) or clobetasol gel for lesions which are easily within reach or dexamethasone (Decadron) elixir (0.5 mg/5ml) to swish around in the mouth for lesions that are in the back of the throat.
- Systemic therapy - Several immune system modifying medications may be used for the more severe cases. These include prednisone either in a short term therapy of 40-80 mg every day for 4-5 days or a long term dosing regimen with gradual taper; pentoxifylline (Trental) 400 mg three times a day for at least 3-6 months and usually for 1 year; colchicine 0.6 mg 2 to 3 times a day, dapsone 100-200 mg daily or azathioprine (Imuran) 50 mg twice daily for 2 weeks. Each of these medications has its own set of side effects which should be weighed against the benefits.
- Pain control therapy - Zilactin which is an over the counter gel, sucralfate(Carafate) to provide a protective coating over the ulcer, or viscous lidocaine 2% to be taken about 20 minutes before meals to reduce the discomfort while eating.
What ever option you chose, please don't do this.
Photo: courtesy of kidshealth.